DELAFIELD, Wis. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.
  
Read More: Warren Buffett's Top 10 Dividend Stocks
Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.
  
Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.
  
With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside.
  
Read More: 5 Stocks Set to Soar on Bullish Earnings
OncoGenex Pharmaceuticals
  
OncoGenex Pharmaceuticals (OGXI), a biopharmaceutical company, develops and commercializes therapies that address treatment resistance in cancer patients. This stock closed up 4% to $3.38 in Tuesday's trading session.
  
Tuesday's Range: $3.25-$3.39
  
52-Week Range: $2.86-$14.25
  
Tuesday's Volume: 268,000
  
Three-Month Average Volume: 211,778
  
From a technical perspective, OGXI ripped higher here right off its 50-day moving average of $3.29 with above-average volume. This move is quickly pushing shares of OGXI within range of triggering a near-term breakout trade. That trade will hit if OGXI manages to take out some key near-term overhead resistance at $3.45 with high volume.
  
Traders should now look for long-biased trades in OGXI as long as it's trending above some near-term support around $3 and then once it sustains a move or close above $3.45 with volume that hits near or above 211,778 shares. If that breakout kicks off soon, then OGXI will set up to re-test or possibly take out its next major overhead resistance levels $3.84 to $4.33. Any high-volume move above those levels will then give OGXI a chance to make a run at $5.
  
Concert Pharmaceuticals
  
Concert Pharmaceuticals (CNCE), a clinical stage biopharmaceutical company, discovers and develops small molecule drugs for central nervous system disorders, renal disease, inflammation and cancer. This stock closed up 5.6% to $9.29 in Tuesday's trading session.
  
Tuesday's Range: $8.80-$9.40
  
52-Week Range: $7.12-$16.26
  
Tuesday's Volume: 136,000
  
Three-Month Average Volume: 156,897
  
From a technical perspective, CNCE ripped sharply higher here right above some near-term support at $8.67 and back above its 50-day moving average of $8.92 with lighter-than-average volume. This strong move to the upside on Tuesday is starting to push shares of CNCE within range of triggering a near-term breakout trade. That trade will hit if CNCE manages to take out Tuesday's intraday high of $9.40 to some more near-term overhead resistance at $9.95 with high volume.
  
Traders should now look for long-biased trades in CNCE as long as it's trending above some key near-term support at $8.67 and then once it sustains a move or close above those breakout levels with volume that hits near or above 156,897 shares. If that breakout gets underway soon, then CNCE will set up to re-test or possibly take out its next major overhead resistance levels at $10.44 to $10.87. Any high-volume move above those levels will then give CNCE a chance to tag $12 to $13.
  
AcelRx Pharmaceuticals
  
AcelRx Pharmaceuticals (ACRX), a development stage specialty pharmaceutical company, focuses on the development and commercialization of therapies for the treatment of acute and breakthrough pain. This stock closed up 4.3% to $6.99 in Tuesday's trading session.
  
Tuesday's Range: $6.64-$7.01
  
52-Week Range: $6.04-$13.64
  
Tuesday's Volume: 723,000
  
Three-Month Average Volume: 1.13 million
  
From a technical perspective, ACRX ripped notably higher here right above some near-term support at $6.50 with lighter-than-average volume. This stock recently formed a double bottom chart pattern at $6.11 to $6.06. Following that bottom, shares of ACRX have started to trend higher and it's now quickly approaching a major breakout trade. That trade will hit if ACRX manages to take out some key near-term overhead resistance levels at $7.15 to its gap-down-day high from July at $7.33 with high volume.
  
Traders should now look for long-biased trades in ACRX as long as it's trending above some near-term support at $6.50 or above those double bottom support levels and then once it sustains a move or close above those breakout levels with volume that hits near or above 1.13 million shares. If that breakout gets underway soon, then ACRX will set up to re-fill some of its recent gap-down-day zone that started at $11.38.
  
CytRx
  
CytRx (CYTR) operates as a biopharmaceutical research and development company specializing in oncology. This stock closed up 3.7% to $3.29 in Tuesday's trading session.
  
Tuesday's Range: $3.17-$3.36
  
52-Week Range: $2.00-$8.35
  
Tuesday's Volume: 973,000
  
Three-Month Average Volume: 1.41 million
  
From a technical perspective, CYTR jumped higher here right above some near-term support at $3.05 with decent upside volume flows. This stock recently formed a double bottom chart pattern at $3.08 to $3.05. Following that bottom, shares of CYTR have started to spike higher and move within range of triggering a big breakout trade. That trade will hit if CYTR manages to take out some near-term overhead resistance levels at $3.42 to its 50-day at $3.66 and then above $3.74 with high volume.
  
Traders should now look for long-biased trades in CYTR as long as it's trending above those double bottom support levels and then once it sustains a move or close above those breakout levels with volume that hits near or above 1.41 million shares. If that breakout develops soon, then CYTR will set up to re-test or possibly take out its next major overhead resistance levels at its 200-day moving average of $4.30 to $4.50.
To see more stocks that are making notable moves higher, check out the Stocks Under $10 Moving Higher portfolio on Stockpickr.
  
-- Written by Roberto Pedone in Delafield, Wis.
  
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  >>3 Stocks Spiking on Unusual Volume  
  >>5 Hated Earnings Stocks You Should Love  
  >>These 5 Toxic Stocks Could Be Poisoning Your Portfolio  
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At the time of publication, author had no positions in stocks mentioned.
  
Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including
CNBC.com and Forbes.com.You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.
 
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Here's a rundown of the week's smartest moves and biggest blunders.    American Apparel (APP) -- Loser    Some retailers are struggling more than others. American Apparel is shaking up its board to try to get a new lease on life, and one of the appointments announced this week was adding RadioShack (RSH) CEO Joseph Magnacca.    Really? RadioShack is one of the few publicly traded retailers with a lower stock price than American Apparel. It's losing gobs of money and closing down stores. Is that really the kind of vision that American Apparel needs in the boardroom? Perhaps more importantly, should RadioShack's CEO be spreading himself thin this way at a time when his own company is struggling just to survive?    American Airlines Group (AAL) -- Winner    There were a lot of milestones achieved by the parent company of American Airlines and US Airways on Thursday. The biggest takeaway from its report is that the adjusted profit of $1.5 billion that it reported for its latest quarter is an all-time record for the once-struggling air carrier. The acquisition of US Airways last year and improving industry fundamentals have gone a long way to improving its fiscal viability.    However, American Airlines Group also initiated a quarterly dividend of 10 cents a share. That may not seem like much, but it's the first time that the airline has offered a cash distribution since 1980. Wow. That was back when folks could still smoke in the back of the plane, and it didn't cost extra to check your luggage.    It's not the only way that American Airlines Group is returning its money to its shareholders. Backed by its healthy profitability, its board cleared the way for a $1 billion stock buyback. Airlines have historically been a wealth destroyer. The cyclical swings in the business can get fierce. However, sector consolidation and an improving global economy make it a compelling place for investors to be in the near term.    Toymakers -- Loser    This was another hard week for the makers of traditional playthings. Hasbro (HAS) shares took a hit on Monday after posting a 12 percent decline in game sales. Other categories were more than enough to offset the weakness in games, but the stock still took a nearly 3 percent stumble on the report.    Two days later it was JAKKS Pacific (JAKK) shares experiencing a nearly 14 percent plunge after it posted uninspiring results. When you combine these two reports with Mattel (MAT) falling out of favor last Friday thanks to a 15 percent drop in Barbie sales, it's easy to get worried about the state of traditional toymakers as we stroll toward the holiday shopping season.    Chipotle Mexican Grill (CMG) -- Winner    We're seeing a lot of eateries drum up excuses for why patrons aren't eating at their establishments anymore, but then we have Chipotle reminding us that it's doing just fine. The fast-casual darling posted blowout quarterly results this week with revenue soaring 29 percent to surpass $1 billion for the first time.    It's not just expansion driving the spike in sales. Comparable-restaurant sales jumped 17.3 percent for the quarter. Chipotle's net income of $3.50 a share landed well ahead of the $3.09 a share that the pros were targeting. Chipotle doesn't need scapegoats when it's rolling like its signature burritos.    General Motors (GM) -- Loser    Another week, another major GM auto recall. The automaker giant is calling back another 717,950 vehicles to correct more safety issues. More than half of the cars in Wednesday's recall involve a potentially defective bolt that adjusts the height of car seats. GM is aware of only a couple of injuries resulting from the bad bolt, but it's yet another embarrassment for the car manufacturer.    GM is now closing in on 30 million cars being recalled this year. It's not just about the near-term financial hit as recall-related costs swallowed up most of GM's profits in its latest quarter. At some point, all of these reports have to hurt the perceived quality of GM's cars.                More from Rick Aristotle Munarriz
  www.hasbro.com    There were plenty of winners and losers this week, including a major airline doing something that it hasn't done in 34 years and more toymakers cutting play time short. Here's a rundown of the week's smartest moves and biggest blunders.    American Apparel (APP) -- Loser    Some retailers are struggling more than others. American Apparel is shaking up its board to try to get a new lease on life, and one of the appointments announced this week was adding RadioShack (RSH) CEO Joseph Magnacca.    Really? RadioShack is one of the few publicly traded retailers with a lower stock price than American Apparel. It's losing gobs of money and closing down stores. Is that really the kind of vision that American Apparel needs in the boardroom? Perhaps more importantly, should RadioShack's CEO be spreading himself thin this way at a time when his own company is struggling just to survive?    American Airlines Group (AAL) -- Winner    There were a lot of milestones achieved by the parent company of American Airlines and US Airways on Thursday. The biggest takeaway from its report is that the adjusted profit of $1.5 billion that it reported for its latest quarter is an all-time record for the once-struggling air carrier. The acquisition of US Airways last year and improving industry fundamentals have gone a long way to improving its fiscal viability.    However, American Airlines Group also initiated a quarterly dividend of 10 cents a share. That may not seem like much, but it's the first time that the airline has offered a cash distribution since 1980. Wow. That was back when folks could still smoke in the back of the plane, and it didn't cost extra to check your luggage.    It's not the only way that American Airlines Group is returning its money to its shareholders. Backed by its healthy profitability, its board cleared the way for a $1 billion stock buyback. Airlines have historically been a wealth destroyer. The cyclical swings in the business can get fierce. However, sector consolidation and an improving global economy make it a compelling place for investors to be in the near term.    Toymakers -- Loser    This was another hard week for the makers of traditional playthings. Hasbro (HAS) shares took a hit on Monday after posting a 12 percent decline in game sales. Other categories were more than enough to offset the weakness in games, but the stock still took a nearly 3 percent stumble on the report.    Two days later it was JAKKS Pacific (JAKK) shares experiencing a nearly 14 percent plunge after it posted uninspiring results. When you combine these two reports with Mattel (MAT) falling out of favor last Friday thanks to a 15 percent drop in Barbie sales, it's easy to get worried about the state of traditional toymakers as we stroll toward the holiday shopping season.    Chipotle Mexican Grill (CMG) -- Winner    We're seeing a lot of eateries drum up excuses for why patrons aren't eating at their establishments anymore, but then we have Chipotle reminding us that it's doing just fine. The fast-casual darling posted blowout quarterly results this week with revenue soaring 29 percent to surpass $1 billion for the first time.    It's not just expansion driving the spike in sales. Comparable-restaurant sales jumped 17.3 percent for the quarter. Chipotle's net income of $3.50 a share landed well ahead of the $3.09 a share that the pros were targeting. Chipotle doesn't need scapegoats when it's rolling like its signature burritos.    General Motors (GM) -- Loser    Another week, another major GM auto recall. The automaker giant is calling back another 717,950 vehicles to correct more safety issues. More than half of the cars in Wednesday's recall involve a potentially defective bolt that adjusts the height of car seats. GM is aware of only a couple of injuries resulting from the bad bolt, but it's yet another embarrassment for the car manufacturer.    GM is now closing in on 30 million cars being recalled this year. It's not just about the near-term financial hit as recall-related costs swallowed up most of GM's profits in its latest quarter. At some point, all of these reports have to hurt the perceived quality of GM's cars.                More from Rick Aristotle Munarriz
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